White Blood Cell Counts, Lymphocyte Subsets, and Incident Diabetes Mellitus in Women Living With and Without HIV.

TitleWhite Blood Cell Counts, Lymphocyte Subsets, and Incident Diabetes Mellitus in Women Living With and Without HIV.
Publication TypeJournal Article
Year of Publication2020
AuthorsJohnston CD, Hoover DR, Shi Q, Sharma A, Hanna DB, Anastos K, Tien PC, Fischl M, Gustafson D, Spence A, Karim R, French A, Schneider M, Adimora AA, Moran C, Konkle-Parker D, Glesby MJ
JournalAIDS Res Hum Retroviruses
Volume36
Issue2
Pagination131-133
Date Published2020 02
ISSN1931-8405
Abstract

Diabetes mellitus (DM) is associated with expansion of proinflammatory lymphocyte subsets. We investigated the relationship of total white blood cell (WBC) count and lymphocyte subsets with incident DM in the Women's Interagency HIV Study (WIHS). Higher CD4 and CD8 T cell counts, lymphocyte count, and total WBC count were associated with incident DM among both women with and without HIV, although the association of CD8 was not statistically significant among women without HIV.

DOI10.1089/AID.2019.0174
Alternate JournalAIDS Res Hum Retroviruses
PubMed ID31709815
PubMed Central IDPMC7044769
Grant ListU01 AI103397 / AI / NIAID NIH HHS / United States
U01 AI031834 / AI / NIAID NIH HHS / United States
U01 AI035004 / AI / NIAID NIH HHS / United States
U01 AI034989 / AI / NIAID NIH HHS / United States
U01 AI034994 / AI / NIAID NIH HHS / United States
U01 AI103401 / AI / NIAID NIH HHS / United States
U01 AI103408 / AI / NIAID NIH HHS / United States
U01 HL146194 / HL / NHLBI NIH HHS / United States
U01 AI103390 / AI / NIAID NIH HHS / United States
U01 AI034993 / AI / NIAID NIH HHS / United States
P30 AI050410 / AI / NIAID NIH HHS / United States
K01 HL137557 / HL / NHLBI NIH HHS / United States
U01 HD032632 / HD / NICHD NIH HHS / United States
U01 AI042590 / AI / NIAID NIH HHS / United States